FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\crqUAS.cFa
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General Information
Symbol
Dmel\crqUAS.cFa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Franc
FlyBase ID
FBal0098761
Feature type
allele
Associated gene
Dmel\crq
Associated Insertion(s)
Carried in Construct
P{UAS-crq.F}
Also Known As
UAS-crq
Key Links
Transgenic product class
wild_type
(Franc et al., 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Franc et al., 1999)
Mutagen
in vitro construct
(Franc et al., 1999)
Progenitor genotype
Carried in construct
P{UAS-crq.F}
Cytology
Description

UAS sequences drive expression of crq.

(Franc et al., 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
crq
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In serial sections of embryos that ubiquitously expressed crqScer\UAS.cFa (driven by Scer\GAL4hs.PB and heatshocked for 1hr at 30oC), apoptotic corpses were not engulfed by cells other than macrophages, thus ectopic expression of crqScer\UAS.cFa is not sufficient to confer phagocytic ability on other cells in the embryo.

      (Franc et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      crqUAS.cFa/Scer\GAL4hs.PU partially rescues Df(2L)al

      (Franc et al., 1999)
      Comments

      crqScer\UAS.cFa driven by Scer\GAL4hs.PB and heatshocked for 1hr at 30oC, in a Df(2L)al homozygote, can partially rescue the phagocytotic phenotype exhibited by the deficiency producing a phagocytic index (PI) for apoptotic corpses of 2.20, as opposed to 0.26 in Df(2L)al homozygotes and 3.96 in wild type.

      (Franc et al., 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      crqScer\UAS.cFa
      crqUAS.cFa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Franc
      (Franc et al., 1999)
      Secondary FlyBase IDs
        References (3)