C-terminal deletion of the Tl10b sequences, to 3681bp.
Expression of Tl10b-Nae.Scer\UAS under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 during the syncytial blastoderm stage results in ventralised embryos; the denticle belts form circumferential rings and the Filzkorpers are strongly reduced or absent.