FlyBase Allele Report: Dmel\JIL-1[Hsp83.GFP]

General Information

Symbol

Dmel\JIL-1^Hsp83.GFP

Species

D. melanogaster

Name

FlyBase ID

FBal0098842

Feature type

allele

Associated gene

Dmel\JIL-1

Associated Insertion(s)

Carried in Construct

P{Hsp83-GFP-JIL-1}

Key Links

Transgenic product class

cDNA

(Jin et al., 1999)

wild_type

(Jin et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Jin et al., 1999)

wild_type

(Jin et al., 1999)

Mutagen

in vitro construct

(Jin et al., 1999)

Progenitor genotype

Carried in construct

P{Hsp83-GFP-JIL-1}

Cytology

Description

The JIL-1 cDNA is fused to GFP coding sequences at its N terminal and driven by Hsp83 promoter.

(Jin et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

Hsp83

Encoded product / tool

JIL-1

Tagged with

GFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

wild-type

(Wang et al., 2001)

Phenotype Manifest In

Detailed Description

Statement

Reference

No indications of dominant-negative effects are observed as a consequence of the overexpression of JIL-1^{Hsp83.T:Avic\GFP}.

(Jin et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

JIL-1^Hsp83.GFP rescues JIL-1^z2

(Bao et al., 2008)

JIL-1^Hsp83.GFP rescues JIL-1^EP3657

(Wang et al., 2001)

JIL-1^Hsp83.GFP rescues JIL-1^z2

(Wang et al., 2001)

Comments

Expression of JIL-1^{Hsp83.T:Avic\GFP} rescues both the autosomal and male X polytene chromosome phenotypes seen in JIL-1^z2 homozygous larvae. The Hsp83 driver is leaky and therefore no heat shock is required.

(Bao et al., 2008)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

JIL-1^Hsp83.GFP

JIL-1^{Hsp83.T:Avic\GFP}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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