FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\NΔECN.sev
Open Close
General Information
Symbol
Dmel\NΔECN.sev
Species
D. melanogaster
Name
FlyBase ID
FBal0101607
Feature type
allele
Associated gene
Dmel\N
Associated Insertion(s)
Carried in Construct
P{sev-NΔECN}
Also Known As
sev-NΔECD
Key Links
Transgenic product class
inframe_deletion
(Periz and Fortini, 1999)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Periz and Fortini, 1999)
Mutagen
in vitro construct
(Periz and Fortini, 1999)
Progenitor genotype
Carried in construct
P{sev-NΔECN}
Cytology
Description

Construct: N coding region carrying a deletion of the entire extracellular domain is expressed from a sev promoter.

(Periz and Fortini, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
N
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of NΔECN.sev results in frequent R4-R4 symmetrical clusters and frequent transformations of outer R1/R6 to inner R7s.

      (Singh and Mlodzik, 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The number of R4-R4 clusters in eyes expressing NΔECN.sev is markedly reduced by co-expression of hbsVDRC.cUa via Scer\GAL4hs.2sev. Notably, even R3-R3 symmetrical clusters, never seen in NΔECN.sev background, are observed in Scer\GAL4hs.2sev>hbsVDRC.cUa, NΔECN.sev.

      (Singh and Mlodzik, 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      NΔECN.sev
      Name Synonyms
      Secondary FlyBase IDs
        References (4)