FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SERCAS5
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General Information
Symbol
Dmel\SERCAS5
Species
D. melanogaster
Name
FlyBase ID
FBal0101766
Feature type
allele
Associated gene
Dmel\SERCA
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Periz and Fortini, 1999)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q108term.

(Suisse and Treisman, 2019)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2R:23,932,227..23,932,227 [-]
Nucleotide change:

C23932227T

Amino acid change:

Q108term | SERCA-PA; Q108term | SERCA-PB; Q108term | SERCA-PC; Q108term | SERCA-PD; Q108term | SERCA-PE; Q108term | SERCA-PF; Q108term | SERCA-PG; Q108term | SERCA-PH; Q108term | SERCA-PI

Reported amino acid change:

Q108term

Comment:

Site and nature of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Suisse and Treisman, 2019)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When clones are induced in the retina homozygous mutant photoreceptors and ommatidia are absent. Adult phenotypes include wing notches and shortened or malformed legs as well as reduced eyes.

      (Periz and Fortini, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Causes dominant eye roughening and maldeposition of lens material between adjacent lenses, typical of the 'facet' mutant phenotype, in a Nl1N-ts1/Nfa-g62 background at 23oC.

      (Periz and Fortini, 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ca-P60AS5
      SERCAS5
      (Suisse and Treisman, 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)