FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\scribhs.PB
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General Information
Symbol
Dmel\scribhs.PB
Species
D. melanogaster
Name
heat shock construct of Bilder
FlyBase ID
FBal0103572
Feature type
allele
Associated gene
Dmel\scrib
Associated Insertion(s)
Carried in Construct
P{hs-scrib.B}
Key Links
Transgenic product class
cDNA
(Bilder and Perrimon, 2000)
wild_type
(Bilder and Perrimon, 2000)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Bilder and Perrimon, 2000)
wild_type
(Bilder and Perrimon, 2000)
Mutagen
in vitro construct
(Bilder and Perrimon, 2000)
Progenitor genotype
Carried in construct
P{hs-scrib.B}
Cytology
Description

Construct: A heat shock promoter drives expression of the scrib A2 cDNA.

(Bilder and Perrimon, 2000)
Allele components
Component
Use(s)
Encoded product / tool
scrib
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      scribhs.PB rescues scribsmi97B

      (Ganguly et al., 2003)

      scribhs.PB rescues scribunspecified

      (Bilder and Perrimon, 2000)
      Comments

      Expression of scribhs.PB using heat shock at 37oC rescues the olfactory behaviour of scribsmi97B adults. scribsmi97B animals carrying scribhs.PB and maintained at 25oC show partial rescue of the scribsmi97B phenotype; the avoidance response to benzaldehyde is restored to normal in males, although females are still significantly smell impaired.

      (Ganguly et al., 2003)

      Rescues the lethality of strong heteroallelic scrib combinations when expressed using heat shock.

      (Bilder and Perrimon, 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      scribhs.PB
      scribhs
      (Ganguly et al., 2003)
      Name Synonyms
      heat shock construct of Bilder
      (Bilder and Perrimon, 2000)
      Secondary FlyBase IDs
        References (2)