FlyBase Allele Report: Dmel\dl[S234P]

General Information

Symbol

Dmel\dl^S234P

Species

D. melanogaster

Name

FlyBase ID

FBal0103850

Feature type

allele

Associated gene

Dmel\dl

Associated Insertion(s)

Carried in Construct

P{dl^S234P}

Key Links

Genomic Maps

JBrowse

Transgenic product class

missense_variant

(Drier et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Drier et al., 2000)

Mutagen

in vitro construct

(Drier et al., 2000)

Progenitor genotype

Carried in construct

P{dl^S234P}

Cytology

Description

Construct: Amino acid replacement: S234P.

(Drier et al., 2000)

Allele components

Component

Use(s)

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

2L:17,442,149..17,442,149 [-]

Nucleotide change:

T17442149C

Amino acid change:

Reported amino acid change:

S234P

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Drier et al., 2000)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryo

(Drier et al., 2000)

Detailed Description

Statement

Reference

One copy of dl^S234P in a wild-type background produces weakly ventralised embryos. One copy of dl^S234P in a dl^unspecified null background produces lateralised embryos.

(Drier et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Other

Statement

Reference

dl^S234P, gd⁸ has embryo phenotype

(Drier et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

One copy of dl^S234P in a gd⁸ background produces dorsalised embryos. The addition of dl^S234P in a dl^unspecified, gd⁸ double null background, produces completely lateralised embryos.

(Drier et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

dl^S234P

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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