FB2026_02 , released June 18, 2026
Allele: Hsap\RAF1Δ305.αTub84B.Tag:Myr(Src64B)
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General Information
Symbol
Hsap\RAF1Δ305.αTub84B.Tag:Myr(Src64B)
Species
H. sapiens
Name
FlyBase ID
FBal0104115
Feature type
allele
Associated gene
Hsap\RAF1
Associated Insertion(s)
Carried in Construct
P{Hsap\RAF1.Δ305.αTub84B}
Key Links
Transgenic product class
inframe_deletion
(Greenwood and Struhl, 1999)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Greenwood and Struhl, 1999)
Mutagen
FLPase
(Greenwood and Struhl, 1999)
Progenitor genotype
Hsap\RAF1Δ305.FRT.αTub84B.Tag:Myr(Src64B)
(Greenwood and Struhl, 1999)
Carried in construct
P{Hsap\RAF1.Δ305.αTub84B}
Cytology
Description

The FRT cassette has been excised, juxtaposing αTub84B promoter sequences with an activated form of Hsap\RAF1 (which contains a 305 amino acid N-terminal truncation), tagged with a myristoylation sequence (Tag:Myr(Src64B)).

(Greenwood and Struhl, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
αTub84B
Encoded product / tool
Hsap\RAF1
Tagged with
Tag:Myr(Src64B)
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Clones of Hsap\RAF1Δ305.αTub84B.T:Myr1 in the adult abdomen do not show any consistent alterations of normal polarity.

      (Lawrence et al., 2002)

      Expression of Hsap\RAF1Δ305.αTub84B.T:Myr1 in the eye disc induces ectopic photoreceptor differentiation just anterior to the morphogenetic furrow.

      (Greenwood and Struhl, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Hsap\RAF1Δ305.αTub84B.T:Myr-Src64B
      Hsap\RAF1Δ305.αTub84B.T:Myr1
      Hsap\RAF1Δ305.αTub84B.Tag:Myr(Src64B)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)