FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Cdk5αUAS.cMa
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General Information
Symbol
Dmel\Cdk5αUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Ma
FlyBase ID
FBal0104348
Feature type
allele
Associated gene
Dmel\Cdk5α
Associated Insertion(s)
Carried in Construct
P{UAS-Cdk5α.M}
Key Links
Transgenic product class
wild_type
(Ma and Haddad, 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Ma and Haddad, 1999)
Mutagen
in vitro construct
(Ma and Haddad, 1999)
Progenitor genotype
Carried in construct
P{UAS-Cdk5α.M}
Cytology
Description

UASt regulatory sequences drive expression of the whole Cdk5α open reading frame.

(Ma and Haddad, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Cdk5α
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The recovery time of young (4 day old) flies to exposure to 5 minutes anoxia is not affected by the expression of Cdk5αScer\UAS.cMa under the control of Scer\GAL4elav.PLu. The recovery time of 15 day old flies to exposure to 5 minutes anoxia is significantly prolonged by the expression of Cdk5αScer\UAS.cMa under the control of Scer\GAL4elav.PLu.

      (Ma and Haddad, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      NOT Enhancer of
      Statement
      Reference

      Cdk5αUAS.cMa, Scer\GAL4GMR.PF is a non-enhancer of visible phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      NOT Suppressor of
      Statement
      Reference

      Cdk5αUAS.cMa, Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      Other
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of both Cdk5Scer\UAS.T:Zzzz\FLAG and Cdk5αScer\UAS.cMa under the control of Scer\GAL4GMR.PF results in a mild rough eye phenotype.

      (Shulman and Feany, 2003)
      Xenogenetic Interactions
      Statement
      Reference

      Co-expression of Cdk5αScer\UAS.cMa alone does not modify the rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF. Co-expression of both Cdk5Scer\UAS.T:Zzzz\FLAG and Cdk5αScer\UAS.cMa together enhances the rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF.

      (Shulman and Feany, 2003)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Cdk5αScer\UAS.cMa
      Cdk5αUAS.cMa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Ma
      (Ma and Haddad, 1999)
      Secondary FlyBase IDs
        References (2)