FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\emshs.PH
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General Information
Symbol
Dmel\emshs.PH
Species
D. melanogaster
Name
heat shock construct of Hartmann
FlyBase ID
FBal0104637
Feature type
allele
Associated gene
Dmel\ems
Associated Insertion(s)
Carried in Construct
P{hs-ems}
Key Links
Transgenic product class
cDNA
(Hartmann et al., 2000)
wild_type
(Hartmann et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Hartmann et al., 2000)
wild_type
(Hartmann et al., 2000)
Mutagen
in vitro construct
(Hartmann et al., 2000)
Progenitor genotype
Carried in construct
P{hs-ems}
Cytology
Description

A 2.2kb ems cDNA fragment is under the control of a heat shock promoter.

(Hartmann et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
ems
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      heatshocked induced ubiquitous expression of emshs.PH before stage 6/7 results in severe developmental defects including malformations in the CNS.

      (Hartmann et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      emshs.PH partially rescues ems2

      (Hartmann et al., 2000)
      Comments

      heatshocked induced ubiquitous expression of emshs.PH in ems2 null mutants, results in a restoration of brain morphology. In a quarter of cases the cellular gap and the longitudinal ganglion are restored. Also a weak restoration of ems labelled commissural and longitudinal axonal projections are observed, though completely wild-type projections are never attained.

      (Hartmann et al., 2000)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      emshs.PH
      Name Synonyms
      heat shock construct of Hartmann
      (Hartmann et al., 2000)
      Secondary FlyBase IDs
        References (1)