FlyBase Allele Report: Dmel\Debcl[GMR.PI]

General Information

Symbol

Dmel\Debcl^GMR.PI

Species

D. melanogaster

Name

glass multimer reporter construct of Igaki

FlyBase ID

FBal0104659

Feature type

allele

Associated gene

Dmel\Debcl

Associated Insertion(s)

Carried in Construct

P{GMR-drob-1}

Key Links

Transgenic product class

cDNA

(Igaki et al., 2000)

wild_type

(Igaki et al., 2000)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Igaki et al., 2000)

wild_type

(Igaki et al., 2000)

Mutagen

in vitro construct

(Igaki et al., 2000)

Progenitor genotype

Carried in construct

P{GMR-drob-1}

Cytology

Description

An EcoRI fragment containing the Debcl cDNA is driven by GMR sequences.

(Igaki et al., 2000)

Allele components

Component

Use(s)

Regulatory region(s)

GMR

engineered transcription regulatory region

Encoded product / tool

Debcl

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible

(Igaki et al., 2000)

Phenotype Manifest In

eye

(Igaki et al., 2000)

eye photoreceptor cell

(Igaki et al., 2000)

ommatidium

(Igaki et al., 2000)

Detailed Description

Statement

Reference

The addition of one copy of P{GMR-drob-1} produces slightly abnormal eyes, increased copies leads top severely rough eyes. There is a loss of photoreceptor morphology and a reduced number or complete loss of the photoreceptor neurons in ommatidia in a gene dosage dependant manner.

(Igaki et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Debcl^GMR.PI has phenotype, non-suppressible by Scer\GAL4^unspecified/Diap2^UAS.cIa

(Igaki et al., 2000)

Debcl^GMR.PI has phenotype, non-suppressible by Dronc^C318G.UAS/Scer\GAL4^unspecified

(Igaki et al., 2000)

Debcl^GMR.PI has phenotype, non-suppressible by Scer\GAL4^unspecified/BacA\p35^UAS.cHa

(Igaki et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Nc^{C318G.Scer\UAS} has little protective effect on the debcl^GMR.PI phenotype even at higher levels.

(Igaki et al., 2000)

Addition of BacA\p35^Scer\UAS.cHa, Iap2^Scer\UAS.cIa or Nc^{C318G.Scer\UAS} has little protective effect on the debcl^GMR.PI phenotype even at higher levels.

(Igaki et al., 2000)

Xenogenetic Interactions

Statement

Reference

Addition of BacA\p35^Scer\UAS.cHa has little protective effect on the debcl^GMR.PI phenotype even at higher levels.

(Igaki et al., 2000)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Debcl^GMR.PI

debcl^GMR.PI

Name Synonyms

glass multimer reporter construct of Igaki

(Igaki et al., 2000)

Secondary FlyBase IDs

References (1)

Report Sections

Open Close