FlyBase Allele Report: Dmel\crol[1ex15]

General Information

Symbol

Dmel\crol^1ex15

Species

D. melanogaster

Name

FlyBase ID

FBal0105036

Feature type

allele

Associated gene

Dmel\crol

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(D'Avino and Thummel, 2000)

Mutagen

Delta2-3 transposase

(D'Avino and Thummel, 2000)

Progenitor genotype

crol⁰⁴⁴¹⁸

(D'Avino and Thummel, 2000)

Cytology

Description

A 2.2kb insertion. Incomplete excision of the P{PZ} insertion in crol⁰⁴⁴¹⁸.

(D'Avino and Thummel, 2000)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

fertile

(D'Avino and Thummel, 2000)

viable

(D'Avino and Thummel, 2000)

Phenotype Manifest In

wing vein | ectopic

(D'Avino and Thummel, 2000)

Detailed Description

Statement

Reference

crol^1ex15 homozygote adults exhibit wing venation phenotypes, including ectopic vein material.

(D'Avino and Thummel, 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Df(2L)esc10, crol^1ex15 has partially lethal - majority die phenotype

(D'Avino and Thummel, 2000)

Phenotype Manifest In

Other

Statement

Reference

Df(2L)esc10, crol^1ex15 has wing phenotype

(D'Avino and Thummel, 2000)

Df(2L)esc10, crol^1ex15 has wing vein | ectopic phenotype

(D'Avino and Thummel, 2000)

Df(2L)esc10, crol^1ex15 has leg phenotype

(D'Avino and Thummel, 2000)

Df(2L)esc10, crol^1ex15 has wing vein phenotype

(D'Avino and Thummel, 2000)

Df(2L)esc10, crol^1ex15 has wing vein L2 | ectopic phenotype

(D'Avino and Thummel, 2000)

Df(2L)esc10, crol^1ex15 has posterior crossvein | ectopic phenotype

(D'Avino and Thummel, 2000)

Additional Comments

Genetic Interactions

Statement

Reference

crol^1ex15 is semilethal in combination with Df(2L)esc10. Only 44% of these animals survive to adulthood, leaving many dead pupae with misshapen legs. In addition half of the survivors have venation defects and 8% have malformed wings. The most common venation defects are ectopic vein material originating from the posterior crossvein and the second longitudinal vein.

(D'Avino and Thummel, 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

crol^1ex15

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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