FB2026_02 , released June 18, 2026
Allele: Dmel\mbo1
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General Information
Symbol
Dmel\mbo1
Species
D. melanogaster
Name
FlyBase ID
FBal0118098
Feature type
allele
Associated gene
Dmel\mbo
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Uv et al., 2000)
Progenitor genotype
mbo05043
(Uv et al., 2000)
Cytology
Description

Almost the entore coding region is deleted.

(Uv et al., 2000)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants fail to pupariate and die as third instar larvae after a prolonged period of larval life. In mutant embryos, 20% of dorsal anastomoses fail to form.

      (Uv et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      mbo1 is a suppressor of lethal phenotype of emb2

      (Roth et al., 2003)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Removal of one copy of mbo1 from emb2 homozygous mutants prolongs the life span of 20% of the individuals to the 3rd instar larval stage (approximately 120 hours after egg laying). This prolonged survival is accompanied by eversion of the anterior spiracles, a morphological characteristic of progression through larval development.

      (Roth et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      mbo2

      (Uv et al., 2000)

      mbo05043

      (Uv et al., 2000)
      Rescued by

      mbo1 is rescued by mbohs.PU

      (Uv et al., 2000)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      mbo-1
      (Uv et al., 2000)
      mbo1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)