FlyBase Allele Report: Dmel\spen[EP2583]

General Information

Symbol

Dmel\spen^EP2583

Species

D. melanogaster

Name

FlyBase ID

FBal0119138

Feature type

allele

Associated gene

Dmel\spen

Associated Insertion(s)

P{EP}spen^EP2583

Carried in Construct

Also Known As

EP(2)2583

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-, Abdelilah-Seyfried et al., 2000)

Progenitor genotype

Associated Insertion(s)

P{EP}spen^EP2583

Cytology

Description

P{EP} insertion within the transcription unit.

(Abdelilah-Seyfried et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | larval stage, with Scer\GAL4^CCAP.PP

(Zhao et al., 2008)

abnormal neuroanatomy | pharate adult stage, with Scer\GAL4^CCAP.PP

(Zhao et al., 2008)

visible, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

dorsocentral bristle | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

larval central nervous system, with Scer\GAL4^CCAP.PP

(Zhao et al., 2008)

neurite | pharate adult stage, with Scer\GAL4^CCAP.PP

(Zhao et al., 2008)

scutellar bristle | ectopic, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

tormogen cell, with Scer\GAL4^sca-537.4

(Abdelilah-Seyfried et al., 2000)

Detailed Description

Statement

Reference

Expression of spen^EP2583 under the control of Scer\GAL4^Ccap.PP results in subtle defects in small portions of the central nervous system arbor in larvae.

Expression of spen^EP2583 under the control of Scer\GAL4^Ccap.PP results in the loss of adult-specific neurite projections.

(Zhao et al., 2008)

Expression of spen^EP2583 under the control of Scer\GAL4^sca-537.4 results in additional scutellar and dorsocentral macrochaetae. Sensory organs with no socket, one shaft/sheath cell are seen.

(Abdelilah-Seyfried et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^sca-537.4, spen^EP2583 has visible phenotype, enhanceable by N^55e11

(Abdelilah-Seyfried et al., 2000)

Suppressed by

Statement

Reference

Scer\GAL4^sca-537.4, spen^EP2583 has visible phenotype, suppressible by H^E21

(Abdelilah-Seyfried et al., 2000)

Phenotype Manifest In

Enhancer of

Statement

Reference

spen^EP2583/Scer\GAL4^sca-537.4 is an enhancer of phenotype of N^55e11

(Abdelilah-Seyfried et al., 2000)

spen^EP2583/Scer\GAL4^sca-537.4 is an enhancer of phenotype of H^E21

(Abdelilah-Seyfried et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

EP(2)2583

(Abdelilah-Seyfried et al., 2000)

spen^EP2583

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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