FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\cpoEP3378
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General Information
Symbol
Dmel\cpoEP3378
Species
D. melanogaster
Name
FlyBase ID
FBal0119281
Feature type
allele
Associated gene
Dmel\cpo
Associated Insertion(s)
P{EP}cpoEP3378
Carried in Construct
Also Known As
EP(3)3378
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-, Fernandez-Funez et al., 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}cpoEP3378
Cytology
Description

The P{EP} insertion is 685bp upstream of the putative ATG start codon in the same orientation to the transcription unit.

(Fernandez-Funez et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No retinal phenotypes are seen when cpoEP3378 is expressed under the control of Scer\GAL4GMR.PU.

      (Branco et al., 2008)

      Expression of cpoEP3378 under the control of Scer\GAL4GMR.PF does not result in a rough eye phenotype.

      (Shulman and Feany, 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Statement
      Reference

      cpoEP3378, Scer\GAL4GMR.PF is a non-enhancer of visible phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      NOT Suppressor of
      Statement
      Reference

      cpoEP3378, Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      Phenotype Manifest In
      Enhancer of
      NOT Enhancer of
      Statement
      Reference

      cpoEP3378, Scer\GAL4GMR.PF is a non-enhancer of eye phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      NOT Suppressor of
      Statement
      Reference

      cpoEP3378, Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of Hsap\MAPTV337M.UAS, Scer\GAL4GMR.PF

      (Shulman and Feany, 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of cpoEP3378 enhances the retinal phenotype seen when Hsap\HTT128Q.1-336.Scer\UAS is expressed under the control of Scer\GAL4GMR.PU.

      Expression of cpoEP3378 enhances the retinal phenotype seen when Hsap\ATXN182Q.Scer\UAS is expressed under the control of Scer\GAL4GMR.PU.

      (Branco et al., 2008)

      The rough eye phenotype caused by expression of Hsap\MAPTV337M.Scer\UAS under the control of Scer\GAL4GMR.PF is not modified if the flies are also carrying cpoEP3378.

      (Shulman and Feany, 2003)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      EP(3)3378
      (Shulman and Feany, 2003)
      cpoEP3378
      Name Synonyms
      Secondary FlyBase IDs
        References (4)