FB2026_02 , released June 18, 2026
Allele: Dmel\hth100-2
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General Information
Symbol
Dmel\hth100-2
Species
D. melanogaster
Name
FlyBase ID
FBal0121727
Feature type
allele
Associated gene
Dmel\hth
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl nitrosourea
(Kurant et al., 2001)
Progenitor genotype
Cytology
Description

Amino acid replacement: R321term.

(Kurant et al., 2001)

Nucleotide substitution: C2213T.

(Kurant et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:10,533,944..10,533,944 [-]
Nucleotide change:

C10533944T

Reported nucleotide change:

C2213T

Amino acid change:

R306term | hth-PA; R321term | hth-PC

Reported amino acid change:

R321term

(Kurant et al., 2001)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutant embryos show a relatively mild phenotype in the PNS, which consists mainly of dorsal localisation of LCh5 neurons in some of the abdominal segments.

      (Kurant et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      hth100-1 and hth100-2 have an identical mutation and are likely to represent a clonal event.

      (Kurant et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      hth100-2
      Name Synonyms
      Secondary FlyBase IDs
        References (1)