FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AmaM109
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General Information
Symbol
Dmel\AmaM109
Species
D. melanogaster
Name
FlyBase ID
FBal0122324
Feature type
allele
Associated gene
Dmel\Ama
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Liebl et al., 2003)
Progenitor genotype
Cytology
Description

Amino acid replacement: C46Y.

(Liebl et al., 2003)

Amino acid replacement: C45Y.

(Liebl et al., 2001)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:6,763,976..6,763,976 [+]
Nucleotide change:

G6763976A

Amino acid change:

C46Y | Ama-PA; C54Y | Ama-PB; C46Y | Ama-PC

Reported amino acid change:

C46Y

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Liebl et al., 2003)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      AmaM109/Ama[+] is an enhancer of abnormal neuroanatomy phenotype of Abl4/Abl1

      (Liebl et al., 2003)

      AmaM109/Ama[+] is an enhancer of lethal phenotype of Abl4/Abl1

      (Liebl et al., 2003)

      Df(3R)ama/AmaM109 is an enhancer of abnormal neuroanatomy phenotype of Abl4/Abl1

      (Liebl et al., 2003)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      AmaM109/Ama[+] is an enhancer of larval ventral nerve cord commissure phenotype of Abl4/Abl1

      (Liebl et al., 2003)

      Df(3R)ama/AmaM109 is an enhancer of larval ventral nerve cord commissure phenotype of Abl4/Abl1

      (Liebl et al., 2003)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Abl1 AmaM109/Df(3R)MAP11 embryos develop normal cuticles. Abl1 AmaM109/Abl4 animals do not survive to the pupal stage. AmaM109/+ increases the frequency of commissure defects in the central nervous system of Abl1/Abl4 embryos; 31% of segments have commissure defects in the double mutant embryos. 86% of segments have commissure defects in the central nervous system of Abl1 AmaM109/Abl4 Df(3R)ama embryos.

      (Liebl et al., 2003)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer

      Induced on: Abl1.

      (Liebl et al., 2003)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      AmaM109
      (Becker et al., 2016)
      amaM109
      (Liebl et al., 2003, Liebl et al., 2001)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)