FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\vtd80Fh-35
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General Information
Symbol
Dmel\vtd80Fh-35
Species
D. melanogaster
Name
FlyBase ID
FBal0123591
Feature type
allele
Associated gene
Dmel\vtd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Schulze et al., 2001, Sinclair et al., 2000)
Progenitor genotype
Cytology
Description

Amino acid replacement: V49E.

(Hallson et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:27,136,757..27,136,757 [+]
Nucleotide change:

T27136757A

Amino acid change:

V49E | vtd-PA; V49E | vtd-PB

Reported amino acid change:

V49E

Comment:

Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.

(Hallson et al., 2008)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Imaginal discs are not evident in vtd80Fh-35/vtdγ26-6, vtd80Fh-35/vtd4 or vtd80Fh-35/Df(3L)K-2 third instar larvae.

      Metaphase chromosome spreads of vtd80Fh-35/vtdγ26-6, vtd80Fh-35/vtd4 and vtd80Fh-35/Df(3L)K-2 third larval instar neuroblasts consist of individual sister chromatids that are not conjoined at the centromere. In addition, the chromosome complements are often aneuploid.

      (Hallson et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      vtd4

      (Schulze et al., 2001)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      vtd80Fh-35 and vtd80Fh-36 contain identical missense mutations and were isolated in the same screen, so it is possible that both derive from the same premeiotic mutagenic event.

      (Hallson et al., 2008)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      35
      (Sinclair et al., 2000)
      vtd35
      (Hallson et al., 2008)
      vtd80Fh-35
      Name Synonyms
      Secondary FlyBase IDs
        References (3)