FB2026_02 , released June 18, 2026
Allele: Dmel\timpFLmut
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General Information
Symbol
Dmel\timpFLmut
Species
D. melanogaster
Name
FlyBase ID
FBal0123668
Feature type
allele
Associated gene
Dmel\tim
Associated Insertion(s)
Carried in Construct
P{timpFLmut}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(McDonald et al., 2001)
Progenitor genotype
timpFL
(McDonald et al., 2001)
Carried in construct
P{timpFLmut}
Cytology
Description

Construct: Nucleotide substitution: A?T. Nucleotide substitution: T?A. Mutation of the E box in the tim promoter sequence.

(McDonald et al., 2001)
Allele components
Component
Use(s)
Encoded product / tool
tim
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Flies carrying timpFLmut in a tim01 background have a period of circadian rhythm activity of 28.2 to 29.5 hours (depending on the line tested).

      (McDonald et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      timpFLmut partially rescues tim01

      (McDonald et al., 2001)
      Comments

      Partially rescues the arrhythmicity of tim01 flies.

      (McDonald et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      timpFLmut
      Name Synonyms
      Secondary FlyBase IDs
        References (1)