FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sliΔL1-L4.UAS
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General Information
Symbol
Dmel\sliΔL1-L4.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0123703
Feature type
allele
Associated gene
Dmel\sli
Associated Insertion(s)
Carried in Construct
P{sli-ΔL1-L4}
Key Links
Transgenic product class
inframe_deletion
(Battye et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Battye et al., 2001)
Mutagen
in vitro construct
(Battye et al., 2001)
Progenitor genotype
sliUAS.cBa
(Battye et al., 2001)
Carried in construct
P{sli-ΔL1-L4}
Cytology
Description

Deletion of sli LRR1, LRR2, LRR3 and most of LRR4; expression is governed by UAS regulatory sequences.

(Battye et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
sli
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When expression of sliScer\UAS.cBa is driven by Scer\GAL4sli.PS, Scer\GAL4elav-C155 or Scer\GAL4en-e16E the ventral nerve cord is unaffected.

      (Battye et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4B2-3-30/sliΔL1-L4.UAS partially rescues sli2

      (MacMullin and Jacobs, 2006)
      Fails to rescue

      sliΔL1-L4.UAS/Scer\GAL4sli.PS fails to rescue sli2

      (Battye et al., 2001)
      Comments

      Expression of sliΔL1-L4.Scer\UAS under the control of Scer\GAL4B2-3-30 leads to a significant recovey in heart cell morphology.

      (MacMullin and Jacobs, 2006)

      Neither midline CNS phenotype nor viability of sli2 are rescued.

      (Battye et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      sliΔL1-L4.Scer\UAS
      sliΔL1-L4.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)