FB2026_02 , released June 18, 2026
Allele: Dmel\Tsc112
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General Information
Symbol
Dmel\Tsc112
Species
D. melanogaster
Name
FlyBase ID
FBal0123969
Feature type
allele
Associated gene
Dmel\Tsc1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Contains a single-base deletion that causes a frameshift, truncating the protein at amino acid 896.

    (Gao and Pan, 2001)

    Deletion of single nucleotide A from position corresponding to nucleotide 3350 of Tsc1+t4.7 rescue fragment.

    (Pan and Levis, 2001.9.10)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    deletion
    3R:24,133,530..24,133,530 [+]
    Comment:

    deletion of single base causes a frameshift

    Comment:

    A single base deletion (an A nucleotide) corresponding to position 3350 of the Tsc[+4.7] rescue fragment that causes a frameshift within amino acid 896.

    Comment:

    A single base deletion within the codon for amino acid 896.

    (Gao and Pan, 2001, Pan and Levis, 2001.9.10)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Tsc112 is rescued by Tsc1+t4.7

        (Gao and Pan, 2001)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Tsc112
        Name Synonyms
        Secondary FlyBase IDs
          References (2)