FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\usp::CtenUsp-1d-c
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General Information
Symbol
Dmel\usp::Cten\Usp-1d-c
Species
D. melanogaster
Name
FlyBase ID
FBal0124917
Feature type
allele
Associated gene
usp::Cten\Usp-1
Associated Insertion(s)
Carried in Construct
P{d/cusp}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Henrich et al., 2000)
Progenitor genotype
Carried in construct
P{d/cusp}
Cytology
Description

Construct: Contains the 5' region of usp - amino acids 1 through 178, and the 3' end of Cten\Usp-1 - amino acids 175 through 451 with a linker of three amino acids between them.

(Henrich et al., 2000)
Allele components
Component
Use(s)
Encoded product / tool
usp::Cten\Usp-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mutants stop development at the larval/prepupal transition. No usp-like phenotypes are seen.

      (Henrich et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      usp::Cten\Usp-1d-c is a suppressor of lethal | larval stage phenotype of usp3

      (Henrich et al., 2000)

      usp::Cten\Usp-1d-c is a suppressor of lethal | larval stage phenotype of usp2

      (Henrich et al., 2000)

      usp::Cten\Usp-1d-c is a suppressor of lethal | larval stage phenotype of usp4

      (Henrich et al., 2000)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The addition of one copy of usp::Cten\Usp-1d-c to usp2, usp3 or usp4 rescues the usp phenotypes, but rescued larvae die at the late third instar stage. Rescued usp2 mutants fail to wander off the food and show no signs of prepupal contraction, although the cuticle becomes partially tanned. Rescued usp3 and usp4 mutants show a cessation of movement during the late third instar, but larvae show no sign of prepupal tanning except along the denticle belts of the midsegments.

      (Henrich et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      usp::Cten\Usp-1d-c
      Name Synonyms
      Secondary FlyBase IDs
        References (1)