FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\sliB1-32
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General Information
Symbol
Dmel\sliB1-32
Species
D. melanogaster
Name
FlyBase ID
FBal0124948
Feature type
allele
Associated gene
Dmel\sli
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Schimmelpfeng et al., 2001)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous embryos have head defects. In stage 17 embryos, the dorsal ectoderm has not reached the anterior tip of the embryo, which remains open, in contrast to wild type.

      (Schimmelpfeng et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      sli[+]/sliB1-32 is an enhancer of abnormal neuroanatomy phenotype of β-Specunspecified

      (Hülsmeier et al., 2007)
      Other
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      sli[+]/sliB1-32 is an enhancer of larval longitudinal connective phenotype of β-Specunspecified

      (Hülsmeier et al., 2007)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Fas2-positive axons occasionally cross the midline in β-Specunspecified stage 16 embryos. The frequency of this phenotype is enhanced if they also carry sliB1-32/+.

      sliB1-32/+ ; α-Specunspecified/α-Specunspecified embryos show ectopic midline-crossing of Fas2-positive axons.

      (Hülsmeier et al., 2007)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      B1-32
      (Schimmelpfeng et al., 2001)
      sliB1-32
      slitB1-32
      (Hülsmeier et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)