FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\βTub56DβTub85D.PR
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General Information
Symbol
Dmel\βTub56DβTub85D.PR
Species
D. melanogaster
Name
β-Tubulin at 85D promoter construct of Raff
FlyBase ID
FBal0125512
Feature type
allele
Associated gene
Dmel\βTub56D
Associated Insertion(s)
Carried in Construct
P{βTub85D-βTub56D.R}
Key Links
Transgenic product class
genomic_DNA
(Raff et al., 2000)
wild_type
(Raff et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Raff et al., 2000)
wild_type
(Raff et al., 2000)
Mutagen
in vitro construct
(Raff et al., 2000)
Progenitor genotype
Carried in construct
P{βTub85D-βTub56D.R}
Cytology
Description

The βTub56D coding region, plus 10bp 5' and 20bp 3' flanking non-coding sequences, is inserted between 2.1 kb 5' and 1.5kb 3' βTub85D genomic sequences. The βTub56D intron is not included.

(Raff et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
βTub85D
Encoded product / tool
βTub56D
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Males carrying one copy of βTub56DβTub85D.PR in a wild-type background are fertile.

      (Hoyle et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Males carrying one copy of βTub56DβTub85D.PR in a βTub85Dn/+ background are fertile. Males carrying one copy of βTub56DβTub85D.PR and one copy of βTub85D432 in a βTub85Dn/+ background are fertile, but have reduced fecundity and a reduced amount of motile sperm compared to wild type.

      (Hoyle et al., 2001)

      The addition of βTub56DβTub85D.PR to βTub85Dn homozygotes the axoneme morphology in testis is abnormal - central pair microtubules are missing and the axoneme is shorter than seen in wild-type.

      (Nielsen et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      βTub56DβTub85D.PR
      Name Synonyms
      β-Tubulin at 85D promoter construct of Raff
      (Nielsen et al., 2001, Raff et al., 2000)
      Secondary FlyBase IDs
        References (3)