FlyBase Allele Report: Dmel\E2f1[unspecified]

General Information

Symbol

Dmel\E2f1^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0126592

Feature type

allele

Associated gene

Dmel\E2f1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die (with E2f1^mir-11-KO.w+)

(Ge et al., 2012)

radiation resistant | maternal effect

(Zhou and Steller, 2003)

viable (with E2f1^mir-11-R.w-)

(Ge et al., 2012)

Phenotype Manifest In

Detailed Description

Statement

Reference

Unlike wild-type, UV irraditaion of pre-gastrula embryos from E2f^unspecified mutant mothers does not induce apoptosis.

(Zhou and Steller, 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

E2f1^unspecified/E2f[+] is an enhancer of visible phenotype of CycE^JP

(Brumby et al., 2004)

NOT Enhancer of

Statement

Reference

E2f1^unspecified is a non-enhancer of visible phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

NOT Suppressor of

Statement

Reference

E2f1^unspecified is a non-suppressor of visible phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

Phenotype Manifest In

Enhancer of

Statement

Reference

E2f1^unspecified/E2f[+] is an enhancer of eye phenotype of CycE^JP

(Brumby et al., 2004)

NOT Enhancer of

Statement

Reference

E2f1^unspecified is a non-enhancer of eye phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

E2f1^unspecified is a non-enhancer of phenotype of png^unspecified

(Lee et al., 2001)

NOT Suppressor of

Statement

Reference

E2f1^unspecified is a non-suppressor of eye phenotype of Myc^UAS.cZa, Scer\GAL4^GMR.PF

(Secombe et al., 2007)

E2f1^unspecified is a non-suppressor of phenotype of png^unspecified

(Lee et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

E2f1^unspecified

E2f^unspecified

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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