FlyBase Allele Report: Dmel\E(To)1[1]

General Information

Symbol

Dmel\E(To)1¹

Species

D. melanogaster

Name

FlyBase ID

FBal0126603

Feature type

allele

Associated gene

E(To)1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Jankovics et al., 2001)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Jankovics et al., 2001)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

E(To)1¹ is an enhancer of some die during embryonic stage | maternal effect | recessive phenotype of Tm1^el4/Tm1^eg9, osk¹

(Jankovics et al., 2001)

Other

Statement

Reference

E(To)1¹, Tm1^eg9, vas^ETo14 has female fertile phenotype

(Jankovics et al., 2001)

E(To)1¹, Tm1^eg9, osk^ETo7 has female sterile phenotype

(Jankovics et al., 2001)

Phenotype Manifest In

Enhancer of

Statement

Reference

E(To)1¹/E(To)1[+] is an enhancer of germline cell phenotype of Tm1^eg20/Tm1^eg9

(Jankovics et al., 2001)

E(To)1¹/E(To)1[+] is an enhancer of embryonic abdominal segment phenotype of Tm1^el4/Tm1^eg9, osk¹

(Jankovics et al., 2001)

E(To)1¹/E(To)1[+] is an enhancer of embryonic abdominal segment phenotype of Tm1^el4/Tm1^eg9, osk[+]/osk¹

(Jankovics et al., 2001)

Other

Statement

Reference

E(To)1¹, Tm1^eg9, osk^ETo7 has embryonic abdominal segment phenotype

(Jankovics et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

Dominantly increases the penetrance of the "posterior group" phenotype of embryos derived from Tm1^eg9 +/Tm1^el4 osk¹ females to 99.6%. Dominantly increases the penetrance of the germ cell-less phenotype of flies derived from Tm1^eg9/Tm1^eg20 females to 95.7%.

(Jankovics et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a dominant enhancer of the Tm1^eg9 +/Tm1^el4 osk¹ phenotype. Separable from: a second lethal mutation on the 3rd chromosome.

(Jankovics et al., 2001)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

E(To)1

(Jankovics et al., 2001)

E(To)1¹

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

Open Close