FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\groCdk1-.UAS
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General Information
Symbol
Dmel\groCdk1-.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0127976
Feature type
allele
Associated gene
Dmel\gro
Associated Insertion(s)
Carried in Construct
P{UAS-gro.Cdk1-}
Key Links
Transgenic product class
missense_variant
(Apidianakis et al., 2001)
polypeptide_post_translational_processing_variant
(Apidianakis et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Apidianakis et al., 2001)
polypeptide_post_translational_processing_variant
(Apidianakis et al., 2001)
Mutagen
in vitro construct
(Apidianakis et al., 2001)
Progenitor genotype
groUAS.cAa
(Apidianakis et al., 2001)
Carried in construct
P{UAS-gro.Cdk1-}
Cytology
Description

UASt sequences drive expression of a gro cDNA which has a mutated Cdk1 phosphorylation site (carries the amino acid replacement S247L).

(Apidianakis et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
gro
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When grocdc2-.Scer\UAS is driven by Scer\GAL4bi-omb-Gal4 pharate lethality is observed and severe shortening of the proximal distal axis of the leg.

      (Apidianakis et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid and transfected into S2 cells.

      (Apidianakis et al., 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      groCdk1-.Scer\UAS
      groCdk1-.UAS
      grocdc2-.Scer\UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (2)