FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\zf30CEP2228
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General Information
Symbol
Dmel\zf30CEP2228
Species
D. melanogaster
Name
FlyBase ID
FBal0128958
Feature type
allele
Associated gene
Dmel\zf30C
Associated Insertion(s)
P{EP}zf30CEP2228
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Cook, 2002.3.7)
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EP}zf30CEP2228
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      zf30CEP2228 in combination with Df(2L)30A-C, Df(2L)γ7, Df(2L)N22-3, Df(2L)s1402, Df(2L)N22-5 or Df(2L)N22-14 gave highly penetrant L5, PCV and L2 shortening. Wings were usually outspread and, in the severest cases, dragged on the ground. Wing margins can be nicked. Females carrying zf30CEP2228 in combination with Df(2L)30A-C, Df(2L)γ7, Df(2L)N22-3, Df(2L)s1402, Df(2L)N22-5 or Df(2L)N22-14 were invariably sterile. Sterile females lay a few nonhatching eggs and had ovaries of normal size with no overt morphological defects.

      (Cook, 2002.3.7)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially complements

      zf30Ck02506

      (Cook, 2002.3.7)
      Comments

      The phenotypes of zf30CEP518 and zf30CEP2228 in combination with zf30Ck02506 were less severe than phenotypes in combination with the deletions. zf30CEP2228/zf30Ck02506 flies showed only weakly penetrant L5 shortening or thinning, and females were fertile. Dp(2;Y)cb50; zf30CEP2228/Df(2L)s1402 males showed a weakly penetrant vein shortening phenotype, and outspread wings. The outspread wing phenotype was more penetrant and pronounced in the presence of the duplication than in its absence.

      (Cook, 2002.3.7)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      The severity of the zf30C alleles can be ranked zf30Ck02506 < zf30CEP518 < zf30CEP2228 in terms of wing phenotype and female sterility. Complements: undΔ34.

      (Cook, 2002.3.7)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      zf30CEP2228
      Name Synonyms
      Secondary FlyBase IDs
        References (2)