FB2026_02 , released June 18, 2026
Allele: Dmel\l(2)dtlKG02590
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General Information
Symbol
Dmel\l(2)dtlKG02590
Species
D. melanogaster
Name
FlyBase ID
FBal0130128
Feature type
allele
Associated gene
Dmel\l(2)dtl
Associated Insertion(s)
P{SUPor-P}l(2)dtlKG02590
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Sloan et al., 2012)
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}l(2)dtlKG02590
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{SUPor-P}
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      BrdU incorporation pattern and levels are not significantly different from wild type in homozygous cycle 15 and 16 embryos.

      Homozygotes progress beyond embryogenesis with intact denticle belts, before dying as larvae. Some larvae survive beyond 4 days after egg deposition and grow to approximately 1.5mm in length, but they are smaller than control larvae.

      0% of embryos laid by wild-type females mated to l(2)dtlKG02590/l(2)dtlf04209 males develop to adulthood.

      4.8 +/- 11% of embryos laid by wild-type females mated to l(2)dtlKG02590/l(2)dtlc02261 males develop to adulthood.

      (Sloan et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Precise excision of the insertion restores male fertility.

      (Sloan et al., 2012)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      KG02590
      (Sloan et al., 2012)
      l(2)dtlKG02590
      Name Synonyms
      Secondary FlyBase IDs
        References (2)