FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\LIMK1UAS.KI.Tag:HA
Open Close
General Information
Symbol
Dmel\LIMK1UAS.KI.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0130966
Feature type
allele
Associated gene
Dmel\LIMK1
Associated Insertion(s)
Carried in Construct
P{UAS-LIMK1.KI}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Niwa et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-LIMK1.KI}
Cytology
Description

UAS sequences drive expression of LIMK1 mutated to a kinase inactive form that has been tagged with Tag:HA.

(Niwa et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
LIMK1
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of LIMK1Scer\UAS.KI.T:Ivir\HA1 under the control of Scer\GAL4Act.PU in olfactory receptor neuron (ORN) clones results in Or59c-expressing ORNs mistargeting in only 10% of cases.

      (Stephan et al., 2012)

      Expression of LIMK1Scer\UAS.KI.T:Ivir\HA1 under the control of Scer\GAL4OK107 results in normal axon projections in the mushroom body.

      (Ng and Luo, 2004)

      Expression of LIMK1Scer\UAS.KI.T:Ivir\HA1 does not cause a detectable wing hair phenotype.

      (Niwa et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      NOT Enhancer of
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of LIMK1Scer\UAS.KI.T:Ivir\HA1 under the control of Scer\GAL4Act.PU significantly rescues the axon mistargeting phenotype seen in Or59c-expressing psidin1 olfactory receptor neuron clones.

      (Stephan et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      LIMK1Scer\UAS.KI.T:Ivir\HA1
      LIMK1UAS.KI.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (5)