FB2026_02 , released June 18, 2026
Allele: Dmel\GαoEP2154
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General Information
Symbol
Dmel\GαoEP2154
Species
D. melanogaster
Name
FlyBase ID
FBal0131023
Feature type
allele
Associated gene
Dmel\Gαo
Associated Insertion(s)
P{EP}GαoEP2154
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EP}GαoEP2154
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The L-type sensilla of homozygous flies show a significantly reduced spike rate in response to sucrose (over a range of concentrations extending from 20 to 500mM) compared to wild-type control sensilla. The mutant L-type sensilla show a normal electrophysiological response to maltose and trehalose, but show a reduced spike rate in response to glucose or fructose.

      Homozygous flies have a reduced ability to distinguish between 5mM and 2mM sucrose in a 2-choice preference assay compared to wild-type controls.

      Homozygotes show a normal avoidance response to caffeine and to quinine in a 2-choice preference assay. The S6 sensilla of these flies show a normal electrophysiological response to caffeine and to quinine.

      (Bredendiek et al., 2011)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      G-oα47AEP2154
      GαoEP2154
      Name Synonyms
      Secondary FlyBase IDs
        References (2)