FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\snf5MER
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General Information
Symbol
Dmel\snf5MER
Species
D. melanogaster
Name
FlyBase ID
FBal0135624
Feature type
allele
Associated gene
Dmel\snf
Associated Insertion(s)
Carried in Construct
P{snf.5MER}
Key Links
Transgenic product class
missense_variant
(Nagengast and Salz, 2001)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Nagengast and Salz, 2001)
Mutagen
in vitro construct
(Nagengast and Salz, 2001)
Progenitor genotype
Carried in construct
P{snf.5MER}
Cytology
Description

Construct: Consists of a mutated RNA binding specificity domain of a wild type snf gene which results in a 5 amino acid change. Amino acid replacement: V40L. Amino acid replacement: A41V. Amino acid replacement: L42S. Amino acid replacement: K43R. Amino acid replacement: T44S.

(Nagengast and Salz, 2001)
Allele components
Component
Use(s)
Encoded product / tool
snf
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Animals carrying the snf5MER mutation are viable, signifying that heterodimer formation with U2A is not essential for viability.

      (Nagengast and Salz, 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The female progeny of snfJ210/+ ; snf5MER females mated to SxlfP7B0/Y males show 98% viability.

      The female progeny of snfJ210/+ ; fl(2)d1/+ ; snf5MER females mated to SxlfP7B0/Y males show 16.1% viability.

      The female progeny of snfJ210/+ ; fl(2)d2/+ ; snf5MER females mated to SxlfP7B0/Y males show 79.3% viability.

      (Penn et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      snf5MER
      Name Synonyms
      Secondary FlyBase IDs
        References (3)