FB2026_02 , released June 18, 2026
Allele: Dmel\Wnt2UAS.cSa
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General Information
Symbol
Dmel\Wnt2UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Struhl
FlyBase ID
FBal0135761
Feature type
allele
Associated gene
Dmel\Wnt2
Associated Insertion(s)
Carried in Construct
P{UAS-Wnt2.S}
Also Known As
UAS-DWnt2
Key Links
Transgenic product class
wild_type
(Llimargas and Lawrence, 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Llimargas and Lawrence, 2001)
Mutagen
in vitro construct
(Llimargas and Lawrence, 2001)
Progenitor genotype
Carried in construct
P{UAS-Wnt2.S}
Cytology
Description

UAS regulatory sequences drive expression of Wnt2.

(Llimargas and Lawrence, 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Wnt2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Animal expressing Wnt2Scer\UAS.cSa when driven by Scer\GAL4αTub84B.PC do not emerge from the puparium. these pharate adults do not exhibit any polarity defects. Wnt2Scer\UAS.cSa when driven by Scer\GAL4ptc-559.1 is lethal.

      (Lawrence et al., 2002)

      Expression of Wnt2Scer\UAS.cSa under the control of Scer\GAL4btl.PS results in hypertrophy of the dorsal trunk in the tracheal system. Expression of Wnt2Scer\UAS.cSa under the control of Scer\GAL4ptc-559.1 does not result in a naked cuticle phenotype.

      (Llimargas and Lawrence, 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Clones of cells in the anterior compartment of the dorsal epidermis of the adult abdomen (in the tergite) that are expressing Wnt2Scer\UAS.cSa under the control of Scer\GAL4αTub84B.PL in a dsunspecified background do not change the cell polarity of cells surrounding the clone.

      (Casal et al., 2006)

      Expression of Wnt2Scer\UAS.cSa under the control of Scer\GAL4wg.PM in a wgl-17 Wnt2unspecified double mutant background rescues some dorsal trunk in the trachea. However when Wnt2Scer\UAS.cSa is expressed under the control of Scer\GAL4btl.PS there is strong rescue, and more dorsal trunk is made.

      (Llimargas and Lawrence, 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      G. Struhl

      (Llimargas and Lawrence, 2001)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Wnt2Scer\UAS.cSa
      (Casal et al., 2006)
      Wnt2UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Struhl
      (Llimargas and Lawrence, 2001)
      Secondary FlyBase IDs
        References (6)