FB2026_03 , released September 17, 2026
Allele: Ecol\lacZaft-22
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General Information
Symbol
Ecol\lacZaft-22
Species
E. coli
Name
FlyBase ID
FBal0136017
Feature type
allele
Associated gene
Ecol\lacZ
Associated Insertion(s)
P{lab-lacZ.1:550.mHMG}Ubc1022
Carried in Construct
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Associated Insertion(s)
    P{lab-lacZ.1:550.mHMG}Ubc1022
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        The P{lab-lacZ.1:550.mHMG}UbcD1022 insertion is within the UbcD10 transcription unit, but Ecol\lacZ expression from the insertion in the tracheal system does not reflect UbcD10 expression, but rather reflects the expression of the aft gene (the P{lab-lacZ.1:550.mHMG}UbcD1022 insertion is 0.8kb downstream of the 3' end of aft). (Note also that Ecol\lacZ expression also occurs in the central midgut endoderm due to the presence of the lab enhancer in the P{lab-lacZ.1:550.mHMG} transgene).

        (Ebner et al., 2002)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        Ecol\lacZaft-22
        Name Synonyms
        Secondary FlyBase IDs
          References (1)