No point mutation is detected in the open reading frame.
Mutant larvae and adults show increased susceptibility to abamectin or ivermectin compared to wild type (viability is reduced). They do not show any increased sensitivity to ethanol compared to wild type. ortP364/Df(3R)12 and ortP364/ort5 adults show increased susceptibility to abamectin compared to wild type (viability is reduced). Mutant adults do not show increased sensitivity to dieldrin compared to wild type. ortP364/Df(3R)12 adults do not show increased sensitivity to dieldrin compared to wild type.