FB2026_03 , released September 17, 2026
Allele: Dmel\dyQ189stop
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General Information
Symbol
Dmel\dyQ189stop
Species
D. melanogaster
Name
FlyBase ID
FBal0138234
Feature type
allele
Associated gene
Dmel\dy
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: Q189term.

    (Jackson, 2002.7.26)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    X:11,772,474..11,772,474 [-]
    Nucleotide change:

    C11772474T

    Reported nucleotide change:

    C1261T

    Amino acid change:

    Q191term | dy-PA

    Reported amino acid change:

    Q?term

    (DiBartolomeis et al., 2002, Jackson, 2002.7.26)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Has no effect on rhythmicity.

        (Jackson, 2002.7.26)

        Mosaics demonstrate a correlation between wing cuticle genotype and the dy phenotype, wings are small if they are included in mutant patches of tissue, and normal if they are included within wild type tissue. dy product acts locally and probably executes a cell-autonomous function to direct wing differentiation.

        (Newby and Jackson, 1995)

        Dusky wing phenotype.

        (Konopka et al., 1991)

        Wing length is shorter than wild type and cell density is higher than wild type. Wing cell boundaries are not visible in homozygotes.

        (Newby et al., 1991)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Separable from: CkIIβAnd.

        (Jackson, 2002.7.26)

        The 'Andante' mutant chromosome carries two independent EMS-induced mutations, one in dy (dyQ189stop) and one in CkIIβ (CkIIβAnd). The dyQ189stop mutation has no effect on rhythmicity, rather the CkIIβAnd allele is responsible for the circadian long-period phenotype of the mutant chromosome.

        (Jackson, 2002.7.26)

        Associated with: CkIIβAnd.

        (Konopka et al., 1991)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (4)
        Reported As
        Symbol Synonym
        dyAnd
        (DiBartolomeis et al., 2002)
        dyG189@
        dyQ189@
        dyQ189stop
        Name Synonyms
        Secondary FlyBase IDs
          References (5)