FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\α-Spec04276
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General Information
Symbol
Dmel\α-Spec04276
Species
D. melanogaster
Name
FlyBase ID
FBal0138601
Feature type
allele
Associated gene
Dmel\α-Spec
Associated Insertion(s)
P{PZ}dlt04276
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{PZ}dlt04276
Cytology
Description

The P{PZ}dlt04276 insertion maps within both α-Spec and dlt (transcription units with non-overlapping ORFs which share untranslated sequences).

(FlyBase Genome Annotators, 2002-2003)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      FlyBase curator comment: the P{PZ}dlt04276 insertion results in homozygous lethality, but since the insertion is within both the α-Spec and dlt transcription units, it is unclear whether the lethality is due to an effect on α-Spec or dlt (or both).

      (Spradling et al., 1999, BDGP Project Members, 1994-1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Complements: l(3)62Be1.

      (BDGP Project Members, 1994-1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      l(3)04276
      (Spradling et al., 1999)
      l(3)0427604276
      (BDGP Project Members, 1994-1999)
      α-Spec04276
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0086960
      References (3)