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General Information
Symbol
Dmel\commUAS.mGFP6
Species
D. melanogaster
Name
FlyBase ID
FBal0141218
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of comm tagged at the C-terminal end with mGFP6.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Single cell leg motoneuron clones expressing commScer\UAS.T:Avic\GFP-m6 induced 48 hr after hatching have the following phenotypes: dendrites shift towards the midline; the mean centre of mass is shifted toward the midline compared to controls; the mean 33rd percentile of arborization is shifted towards the midline.

Single cell leg motoneuron clones expressing commScer\UAS.T:Avic\GFP-m6 induced 96 hr after hatching have the following phenotypes: dendrites enter medial territories within the neuropil with several branches terminating on the midline; the mean centre of mass is shifted toward the midline compared to controls; the mean 33rd percentile of arborization is shifted towards the midline. In a dorsoventral plane, these clones show a redistribution of dendrites into posterior and very dorsal neuropil, whilst arbor is entirely lost from ventral domains.

Pan-neural expression of one copy of commScer\UAS.T:Avic\GFP-m6 under the control of Scer\GAL4unspecified results in a robo phenocopy in which a subset of longitudinal axons are misdirected across the midline. Pan-neural expression of two copies of commScer\UAS.T:Avic\GFP-m6 under the control of Scer\GAL4unspecified results in sli phenocopy in which the majority of axons extend at the midline.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
commScer\UAS.T:Avic\GFP-m6
commUAS.mGFP6
Name Synonyms
Secondary FlyBase IDs
    References (3)