When Bx42^{dsRNA.Scer\UAS} is driven by Scer\GAL4^T80, embryos develop beyond gastrulation, the majority of embryos die at extended germ band stage having failed to develop any cuticle. About 5% of these embryos exhibit a neurogenic phenotype and only dorsal cuticle is produced. The remaining embryos show variable phenotypes like segmentation and head defects. When Bx42^{dsRNA.Scer\UAS} is driven by Scer\GAL4^αTub84B.PL, 50% embryonic lethality is seen. When Bx42^{dsRNA.Scer\UAS} is driven by Scer\GAL4^G6.1, mutant females develop only very tiny secretory lobes, if they develop any at all. However they still have small excretion ducts. Only 20% of the expected females hatch, but those that do are fertile. When Bx42^{dsRNA.Scer\UAS} is driven by Scer\GAL4^ey.PH mutants mostly die as pupae. Escapers eclose at a low rate with one or both of their compound eyes split into parts, strongly reduced in size or completely absent. Sometimes, parts of their eyes or the whole eye are transformed into ectopic antennae, often forming all antennal segments including the aristae. Unhatched animals exhibit stronger phenotypes. In some such animals head structures are completely missing and the remaining mouthparts originating from the gnathal segment are fused to the thorax. In other animals both the head and gnathal segment derivatives are missing. When Bx42^{dsRNA.Scer\UAS} is driven by Scer\GAL4^ptc-559.1 at 25^oC loss of both the anterior and posterior scutellar bristles is seen. The anterior crossvein, and occasionally wing vein L3, is missing in mutant wings. Other defects (including duplication of leg segments) are sometimes seen. Induction at 29^oC is lethal. When Bx42^{dsRNA.Scer\UAS} is driven by Scer\GAL4^dpp.blk1 at 25^oC and below no detectable phenotypic consequences are seen. When driven at 29^oC however, deletions in wing vein L3 and in the distal wing and deletion of the anterior cross vein are seen. In addition, the wing field between veins L3 and L4 is diminished and the thickness of the veins is reduced.

Bx42^RNAi.UAS.cNa, Scer\GAL4^dpp.blk1, Su(H)^UAS.cKa has wing phenotype