FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\rhoNeo.UAS
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General Information
Symbol
Dmel\rhoNeo.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0143268
Feature type
allele
Associated gene
Dmel\rho
Associated Insertion(s)
Carried in Construct
P{UAS-rho.Neo.Δ}
Key Links
Transgenic product class
gain_of_function_variant
(Guichard et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
gain_of_function_variant
(Guichard et al., 2002)
Mutagen
Delta2-3 transposase
(Guichard et al., 2002)
Progenitor genotype
rhoUAS.cBa
(Guichard et al., 2002)
Carried in construct
P{UAS-rho.Neo.Δ}
Cytology
Description

Incorrect excision of P{UAS-ve.B} produced P{UAS-Rho.Neo.Δ}, which has a 5kb deletion removing parts of both the rho cDNA and the adjacent w+mC gene. It is predicted to encode a truncated protein containing the first 140 amino acids of rho and 10 amino acids encoded out-of-frame by the 3' end of w, which are fused to the rho coding sequence.

(Guichard et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
rho
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      rhoNeo.Scer\UAS; Scer\GAL4Bx-MS1096 flies have small blistered wings with thickened veins and margin defects. In extreme cases, wings are virtually absent. rhoNeo.Scer\UAS; Scer\GAL4vg.int2.1 flies exhibit wing notching (patchy loss of margin and adjacent wing tissue).

      (Guichard et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4Bx-MS1096, rhoNeo.UAS has wing margin phenotype, suppressible by NAx-1/N[+]

      (Guichard et al., 2002)

      Scer\GAL4Bx-MS1096, rhoNeo.UAS has wing vein phenotype, suppressible by NAx-1/N[+]

      (Guichard et al., 2002)

      Scer\GAL4Bx-MS1096, rhoNeo.UAS has wing phenotype, suppressible by NAx-1/N[+]

      (Guichard et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      All wing phenotypes of rhoNeo.Scer\UAS; Scer\GAL4Bx-MS1096 flies are strongly suppressed by NAx-1/+.

      (Guichard et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      rhoNeo.Scer\UAS
      rhoNeo.UAS
      rhoNeo
      (Guichard et al., 2002)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)