FlyBase Allele Report: Dmel\rho[UAS.cBa]

General Information

Symbol

Dmel\rho^UAS.cBa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Bier

FlyBase ID

FBal0090071

Feature type

allele

Associated gene

Dmel\rho

Associated Insertion(s)

Carried in Construct

P{UAS-ve.B}

Also Known As

UAS-rho

Key Links

Transgenic product class

wild_type

(Buff et al., 1998)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Buff et al., 1998)

Mutagen

in vitro construct

(Buff et al., 1998)

Progenitor genotype

Carried in construct

P{UAS-ve.B}

Cytology

Description

UAS regulatory sequences drive expression of rho.

(Buff et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

rho

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Phenotype Manifest In

Detailed Description

Statement

Reference

rho^Scer\UAS.cBa; Scer\GAL4^GMR.PF adults have rough eyes and the proportion of ommatidia with pale-type R8 cells is significantly increased. Many of these cells are found in ommatidia with a yellow-type R7.

(Birkholz et al., 2009)

In rho^Scer\UAS.cBa; Scer\GAL4^sim.PS embryos, about a fifth of ganglionic tracheal branch 1s turn posteriorly prematurely, before reaching their characteristic positions close to the midline. Ganglionic branch 1s turn prematurely before reaching the midline in rho^Scer\UAS.cBa; Scer\GAL4^bs-23.26 embryos. Longitudinal fascicles of the ventral nerve cord appear normal in these embryos.

(Gallio et al., 2004)

The wings of rho^Scer\UAS.cBa; Scer\GAL4^Bx-MS1096 flies have ectopic vein material.

(Guichard et al., 2002)

When stet^Scer\UAS.cGa is driven by Scer\GAL4^CY2 a strong dorsalisation of the eggshell is seen, resulting in a fused dorsal appendage covering the anterior end of the egg.

(Guichard et al., 2000)

Misexpression of rho^Scer\UAS.cBa driven by Scer\GAL4^Bx-MS1096 converts almost the entire wing blade into solid vein material and dramatically reduces the size of the wing.

(Guichard et al., 1999)

Embryos expressing rho^Scer\UAS.cBa under the control of Scer\GAL4^twi.PG show a marked overproduction of eve-positive mesodermal founder cells.

(Buff et al., 1998)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, rho^UAS.cBa has visible phenotype, suppressible by Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

NOT Enhancer of

Statement

Reference

rho^UAS.cBa, Scer\GAL4^Bx-MS1096 is a non-enhancer of visible phenotype of Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

rho^UAS.cBa/vn^UAS.cSa, Scer\GAL4^Bx-MS1096 is a non-enhancer of visible phenotype of Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

rho^UAS.cBa/S^UAS.cGb, Scer\GAL4^Bx-MS1096 is a non-enhancer of visible phenotype of Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Suppressor of

Statement

Reference

rho^UAS.cBa/Scer\GAL4^kni.L2 is a suppressor of visible phenotype of kni^ri-1

(Lunde et al., 2003)

NOT Suppressor of

Statement

Reference

rho^UAS.cBa, Scer\GAL4^Bx-MS1096 is a non-suppressor of visible phenotype of Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

rho^UAS.cBa/vn^UAS.cSa, Scer\GAL4^Bx-MS1096 is a non-suppressor of visible phenotype of Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

rho^UAS.cBa/S^UAS.cGb, Scer\GAL4^Bx-MS1096 is a non-suppressor of visible phenotype of Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Other

Statement

Reference

S^UAS.cGb, Scer\GAL4^kni.L2, rho^UAS.cBa has visible phenotype

(Lunde et al., 2003)

Egfr^UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has visible phenotype

(Guichard et al., 1999)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L3 phenotype, non-enhanceable by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L4 phenotype, non-enhanceable by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L5 phenotype, non-enhanceable by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing phenotype, non-enhanceable by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein phenotype, non-enhanceable by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L3 phenotype, non-enhanceable by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L4 phenotype, non-enhanceable by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L5 phenotype, non-enhanceable by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing phenotype, non-enhanceable by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein phenotype, non-enhanceable by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein phenotype, suppressible by S^DN.UAS, Scer\GAL4^Bx-MS1096

(Guichard et al., 2002)

Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein | ectopic phenotype, suppressible | partially by S^X155/S[+]

(Guichard et al., 1999)

Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein | ectopic | somatic clone phenotype, suppressible by S^X155

(Guichard et al., 1999)

Scer\GAL4^twi.PG, rho^UAS.cBa has muscle founder cell | embryonic stage phenotype, suppressible | partially by Egfr^DN.UAS.cBa, Scer\GAL4^twi.PG

(Buff et al., 1998)

NOT suppressed by

Statement

Reference

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing phenotype, non-suppressible by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein phenotype, non-suppressible by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L3 phenotype, non-suppressible by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L4 phenotype, non-suppressible by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L5 phenotype, non-suppressible by S^UAS.cGb, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing phenotype, non-suppressible by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein phenotype, non-suppressible by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L3 phenotype, non-suppressible by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L4 phenotype, non-suppressible by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein L5 phenotype, non-suppressible by vn^UAS.cSa, Scer\GAL4^Bx-MS1096

(Guichard et al., 1999)

NOT Enhancer of

Statement

Reference

rho^UAS.cBa, Scer\GAL4^Bx-MS1096 is a non-enhancer of wing phenotype of Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 2000)

Suppressor of

Statement

Reference

rho^UAS.cBa/Scer\GAL4^elav.PLu is a suppressor of embryonic/larval ganglionic tracheal branch phenotype of ru^unspecified

(Gallio et al., 2004)

rho^UAS.cBa/Scer\GAL4^sim.PS is a suppressor of embryonic/larval ganglionic tracheal branch phenotype of ru^unspecified

(Gallio et al., 2004)

rho^UAS.cBa/Scer\GAL4^sli.PS is a suppressor of embryonic/larval ganglionic tracheal branch phenotype of ru^unspecified

(Gallio et al., 2004)

rho^UAS.cBa/Scer\GAL4^kni.L2 is a suppressor of wing vein L2 phenotype of kni^ri-1

(Lunde et al., 2003)

rho^UAS.cBa/Scer\GAL4^{VP16.nanos.UTR} is a suppressor | partially of testis phenotype of stet^unspecified

(Schulz et al., 2002)

NOT Suppressor of

Statement

Reference

rho^UAS.cBa, Scer\GAL4^Bx-MS1096 is a non-suppressor of wing phenotype of Egfr^DN.UAS.cBa, Scer\GAL4^Bx-MS1096

(Guichard et al., 2000)

Other

Statement

Reference

S^UAS.cGb, Scer\GAL4^kni.L2, rho^UAS.cBa has wing phenotype

(Lunde et al., 2003)

S^UAS.cGb, Scer\GAL4^kni.L2, rho^UAS.cBa has wing vein | ectopic phenotype

(Lunde et al., 2003)

Egfr^UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing phenotype

(Guichard et al., 1999)

Egfr^UAS.cBa, Scer\GAL4^Bx-MS1096, rho^UAS.cBa has wing vein phenotype

(Guichard et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

rho^Scer\UAS.cBa; Scer\GAL4^sli.PS and rho^Scer\UAS.cBa; Scer\GAL4^sim.PS partially suppress ventral midline crossing by ganglionic tracheal branches in ru^unspecified mutant stage 16 embryos.

(Gallio et al., 2004)

Expression of rho^Scer\UAS.cBa under the control of Scer\GAL4^kni.L2 rescues the L2 wing vein phenotype of kni^ri-1 flies. Co-expression of S^Scer\UAS.cGb and rho^Scer\UAS.cBa under the control of Scer\GAL4^kni.L2 results in ectopic veins that are displaced from the endogenous L2 wing vein by a few cells.

(Lunde et al., 2003)

Co-expression of Egfr^{DN.Scer\UAS.cBa} and rho^Scer\UAS.cBa driven by Scer\GAL4^Bx-MS1096 in females deletes parts of dorsal veins L3, L5 and the distal portion of L4, reduces the width of the wing, and causes mis-alignment between dorsal and ventral components of the veins. This is an almost identical phenotype to Scer\GAL4^Bx-MS1096 driven Egfr^{DN.Scer\UAS.cBa} expression alone. In males a stronger vein-loss phenotype is seen. Co-expression of Egfr^{DN.Scer\UAS.cBa}, Egfr^Scer\UAS.cBa and rho^Scer\UAS.cBa driven by Scer\GAL4^Bx-MS1096 fully restores the rho^Scer\UAS.cBa induced ectopic vein phenotype. Overexpression of rho^Scer\UAS.cBa driven by Scer\GAL4^Bx-MS1096 in S^X155 heterozygotes, leads to a partial suppression of the rho^Scer\UAS.cBa induced solid vein phenotype. Overexpression of rho^Scer\UAS.cBa driven by Scer\GAL4^Bx-MS1096 in S^X155 homozygous clones, produced a S^X155 type phenotype, the rho^Scer\UAS.cBa induced solid wing phenotype is completely suppressed.

(Guichard et al., 1999)

The overproduction of eve-positive mesodermal founder cells seen in embryos expressing rho^Scer\UAS.cBa under the control of Scer\GAL4^twi.PG is partly suppressed if they are also carrying Egfr^{DN.Scer\UAS.cBa}.

(Buff et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

E. Bier

(Buff et al., 1998)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

rho^Scer\UAS.cBa

rho^UAS.cBa

ve^Scer\UAS.cBa

(Guichard et al., 1999)

ve^UAS.cBa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Bier

(Buff et al., 1998)

Secondary FlyBase IDs

References (11)

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