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General Information
Symbol
Dmel\rhoUAS.cBa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Bier
FlyBase ID
FBal0090071
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-rho
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of rho.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

rhoScer\UAS.cBa; Scer\GAL4GMR.PF adults have rough eyes and the proportion of ommatidia with pale-type R8 cells is significantly increased. Many of these cells are found in ommatidia with a yellow-type R7.

In rhoScer\UAS.cBa; Scer\GAL4sim.PS embryos, about a fifth of ganglionic tracheal branch 1s turn posteriorly prematurely, before reaching their characteristic positions close to the midline. Ganglionic branch 1s turn prematurely before reaching the midline in rhoScer\UAS.cBa; Scer\GAL4bs-23.26 embryos. Longitudinal fascicles of the ventral nerve cord appear normal in these embryos.

The wings of rhoScer\UAS.cBa; Scer\GAL4Bx-MS1096 flies have ectopic vein material.

When stetScer\UAS.cGa is driven by Scer\GAL4CY2 a strong dorsalisation of the eggshell is seen, resulting in a fused dorsal appendage covering the anterior end of the egg.

Misexpression of rhoScer\UAS.cBa driven by Scer\GAL4Bx-MS1096 converts almost the entire wing blade into solid vein material and dramatically reduces the size of the wing.

Embryos expressing rhoScer\UAS.cBa under the control of Scer\GAL4twi.PG show a marked overproduction of eve-positive mesodermal founder cells.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
NOT Enhanced by
Suppressed by
NOT suppressed by
NOT Enhancer of
Statement
Reference
Suppressor of
NOT Suppressor of
Statement
Reference
Other
Additional Comments
Genetic Interactions
Statement
Reference

rhoScer\UAS.cBa; Scer\GAL4sli.PS and rhoScer\UAS.cBa; Scer\GAL4sim.PS partially suppress ventral midline crossing by ganglionic tracheal branches in ruunspecified mutant stage 16 embryos.

Expression of rhoScer\UAS.cBa under the control of Scer\GAL4kni.L2 rescues the L2 wing vein phenotype of kniri-1 flies. Co-expression of SScer\UAS.cGb and rhoScer\UAS.cBa under the control of Scer\GAL4kni.L2 results in ectopic veins that are displaced from the endogenous L2 wing vein by a few cells.

Co-expression of EgfrDN.Scer\UAS.cBa and rhoScer\UAS.cBa driven by Scer\GAL4Bx-MS1096 in females deletes parts of dorsal veins L3, L5 and the distal portion of L4, reduces the width of the wing, and causes mis-alignment between dorsal and ventral components of the veins. This is an almost identical phenotype to Scer\GAL4Bx-MS1096 driven EgfrDN.Scer\UAS.cBa expression alone. In males a stronger vein-loss phenotype is seen. Co-expression of EgfrDN.Scer\UAS.cBa, EgfrScer\UAS.cBa and rhoScer\UAS.cBa driven by Scer\GAL4Bx-MS1096 fully restores the rhoScer\UAS.cBa induced ectopic vein phenotype. Overexpression of rhoScer\UAS.cBa driven by Scer\GAL4Bx-MS1096 in SX155 heterozygotes, leads to a partial suppression of the rhoScer\UAS.cBa induced solid vein phenotype. Overexpression of rhoScer\UAS.cBa driven by Scer\GAL4Bx-MS1096 in SX155 homozygous clones, produced a SX155 type phenotype, the rhoScer\UAS.cBa induced solid wing phenotype is completely suppressed.

The overproduction of eve-positive mesodermal founder cells seen in embryos expressing rhoScer\UAS.cBa under the control of Scer\GAL4twi.PG is partly suppressed if they are also carrying EgfrDN.Scer\UAS.cBa.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
rhoScer\UAS.cBa
rhoUAS.cBa
veScer\UAS.cBa
veUAS.cBa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Bier
Secondary FlyBase IDs
    References (11)