FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\SDN.UAS
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General Information
Symbol
Dmel\SDN.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0144612
Feature type
allele
Associated gene
Dmel\S
Associated Insertion(s)
Carried in Construct
P{UAS-S.DN}
Key Links
Transgenic product class
dominant_negative_variant
(Guichard et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
dominant_negative_variant
(Guichard et al., 2002)
Mutagen
Delta2-3 transposase
(Guichard et al., 2002)
Progenitor genotype
SUAS.cGb
(Guichard et al., 2002)
Carried in construct
P{UAS-S.DN}
Cytology
Description

An internal inversion in P{UAS-Star.G} with break-points within the S coding region and its 3' UTR, has produced a transgene in which S, truncated at aa 124, is under the control of UAS sequences.

(Guichard et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
S
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      SDN.Scer\UAS; Scer\GAL4Bx-MS1096 flies lack the distal portions of their longitudinal wing veins. This phenotype is much more pronounced in SDN.Scer\UAS/SDN.Scer\UAS; Scer\GAL4Bx-MS1096 flies, which can exhibit almost complete loss of L2.

      (Guichard et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhanced by
      Statement
      Reference

      SDN.UAS, Scer\GAL4Bx-MS1096 has wing vein phenotype, enhanceable by grkUAS.cQa, Scer\GAL4Bx-MS1096

      (Guichard et al., 2002)
      Suppressor of
      Statement
      Reference

      SDN.UAS, Scer\GAL4Bx-MS1096 is a suppressor of wing vein phenotype of Scer\GAL4Bx-MS1096, rhoUAS.cBa

      (Guichard et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The vein truncation phenotype seen in SDN.Scer\UAS; Scer\GAL4Bx-MS1096 flies is enhanced by the presence of grkScer\UAS.cQa.

      (Guichard et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      SDN.UAS is rescued by Scer\GAL4Bx-MS1096/SUAS.cGb

      (Guichard et al., 2002)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SDN.Scer\UAS
      SDN.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)