FlyBase Allele Report: Dmel\mei-P22[unspecified]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\mei-P22^unspecified

General Information

Symbol

Dmel\mei-P22^unspecified

Species

D. melanogaster

Name

FlyBase ID

FBal0143328

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

FlyBase curator comment: this entry is used to capture phenotypic information when the particular allele (or allele combination) used by the author could not be determined but the context of the experiment suggests that the phenotype being described is some kind of loss of function.

(FlyBase Curators, 2025-)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

karyosome | oogenesis

(Joshi et al., 2024)

(Joshi et al., 2024)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressed by

Statement

Reference

mei-P22^unspecified has karyosome | oogenesis phenotype, suppressible | partially by Scer\GAL4^unspecified/Spc105R^GL00392

(Joshi et al., 2024)

mei-P22^unspecified has oocyte phenotype, suppressible | partially by Scer\GAL4^unspecified/Spc105R^GL00392

(Joshi et al., 2024)

mei-P22^unspecified has karyosome | oogenesis phenotype, suppressible | partially by Ndc80^GL00625/Scer\GAL4^unspecified/Spc105R^GL00392/Spc105R^{ΔMELT-KI.UASp.RR}

(Joshi et al., 2024)

mei-P22^unspecified has oocyte phenotype, suppressible | partially by Ndc80^GL00625/Scer\GAL4^unspecified/Spc105R^GL00392/Spc105R^{ΔMELT-KI.UASp.RR}

(Joshi et al., 2024)

Suppressor of

Statement

Reference

mei-P22^unspecified/mei-P22^unspecified is a suppressor of karyosome phenotype of Brca2^KO/Brca2^56E

(Klovstad et al., 2008)

mei-P22^unspecified/mei-P22^unspecified is a suppressor of dorsal appendage phenotype of Brca2^KO/Brca2^56E

(Klovstad et al., 2008)

mei-P22^unspecified is a suppressor of phenotype of okr^unspecified

(Ghabrial and Schupbach, 1999)

Other

Statement

Reference

Ndc80^GL00625, Scer\GAL4^unspecified, mei-P22^unspecified has oocyte phenotype

(Joshi et al., 2024)

Ndc80^GL00625, Scer\GAL4^unspecified, mei-P22^unspecified has karyosome | oogenesis phenotype

(Joshi et al., 2024)

Mis12::Spc105R^{N-MIS12.UASp.RR}, Scer\GAL4^unspecified, Spc105R^GL00392, mei-P22^unspecified has oocyte phenotype

(Joshi et al., 2024)

Mis12::Spc105R^{N-MIS12.UASp.RR}, Scer\GAL4^unspecified, Spc105R^GL00392, mei-P22^unspecified has karyosome | oogenesis phenotype

(Joshi et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

The eggshell patterning and karyosome formation defects of Brca2^KO/Brca2^56E females are rescued by mei-P22^unspecified/mei-P22^unspecified.

(Klovstad et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mei-P22^unspecified

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections