FlyBase Allele Report: Dmel\Ofut1[SH2260]

General Information

Symbol

Dmel\Ofut1^SH2260

Species

D. melanogaster

Name

FlyBase ID

FBal0143448

Feature type

allele

Associated gene

Dmel\Ofut1

Associated Insertion(s)

P{lacW}Ofut1^SH2260

Carried in Construct

Also Known As

Ofut1^SH

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Oh et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{lacW}Ofut1^SH2260

Cytology

Description

Insertion in the 3' end of O-fut1 which is predicted to result in replacement of the seven C-terminal amino acids (TNVHEEL) with four different amino acids (DEIT) followed by a stop codon.

(Okajima et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2R:14,162,430..14,162,699

(Oh et al., 2003, Okajima et al., 2003)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal | recessive

(Oh et al., 2003)

visible | recessive | somatic clone

(Okajima et al., 2003)

Phenotype Manifest In

macrochaeta | somatic clone

(Okajima et al., 2003)

scutellar bristle | somatic clone

(Okajima et al., 2003)

wing | somatic clone

(Okajima et al., 2003)

wing vein | somatic clone

(Okajima et al., 2003)

Detailed Description

Statement

Reference

Homozygous clones result in loss of wing tissue, thickening of the wing veins and loss of sensory bristles on the notum (including the loss of scutellar bristles).

(Okajima et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

51666

w^*; P{lacW}Ofut1^SH2260/CyO

Kyoto

122121

w^*; P{lacW}Ofut1^SH2260

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

O-fut1^SH2260

(Shi et al., 2021)

Ofut1^SH2260

Ofut1^SH

(Okajima et al., 2005, Okajima et al., 2003)

Ofut1^sh

(Lowe, 2005)

l(2)SH2260

(Okajima et al., 2003)

l(2)SH2260^SH2260

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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