FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\hydK7.19
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General Information
Symbol
Dmel\hydK7.19
Species
D. melanogaster
Name
FlyBase ID
FBal0144234
Feature type
allele
Associated gene
Dmel\hyd
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: R252term.

    (Moncrieff et al., 2015)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    3R:9,723,864..9,723,864 [-]
    Nucleotide change:

    C9723864T

    Amino acid change:

    R252term | hyd-PA; R252term | hyd-PB

    Reported amino acid change:

    R252term

    Comment:

    Site and nature of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

    (Moncrieff et al., 2015)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Some mutant clones in the posterior compartment of the wing disc are rounded in shape and show overgrowth.

        (Lee et al., 2002)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        hydK7.19 atoIH3 double mutant clones in the eye disc do not differentiate, but can induce ectopic photoreceptor differentiation in surrounding wild-type tissue. hydK7.19 clones in the eye disc which are also expressing ci76.Scer\UAS under the control of Scer\GAL4αTub84B.PL sometimes result in ectopic photoreceptor differentiation in the tissue surrounding the clone. hydK7.19 hhrJ413 double mutant clones in the eye which are also expressing ci76.Scer\UAS under the control of Scer\GAL4αTub84B.PL do not show overgrowth.

        (Lee et al., 2002)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (1)
        Reported As
        Symbol Synonym
        hydK7.19
        (Moncrieff et al., 2015)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)