FB2025_01 , released February 20, 2025
Allele: Dmel\Wnt5EY03178
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General Information
Symbol
Dmel\Wnt5EY03178
Species
D. melanogaster
Name
FlyBase ID
FBal0144485
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Associated Insertion(s)
Cytology
Description

The P{EPgy2} insertion is 23bp upstream of the transcriptional start site for Wnt5.

Allele components
Component
Use(s)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When Wnt5EY03178 is driven by Scer\GAL4sim.PS a marked reduction or complete loss of anterior commissures (ACs) is seen in 43% of segments. The affected AC axons appear to stall or project ipsilaterally within the longitudinal connectives.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The addition of homozygous drlRed2 to Wnt5EY03178, drlRed2 embryos completely suppresses the loss of anterior commissures (ACs), although abnormal projections between the ACs and the posterior commissures remain.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Wnt5EY03178
Name Synonyms
Secondary FlyBase IDs
    References (1)