FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\pavDEAD.UASp.mGFP6
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General Information
Symbol
Dmel\pavDEAD.UASp.mGFP6
Species
D. melanogaster
Name
FlyBase ID
FBal0146932
Feature type
allele
Associated gene
Dmel\pav
Associated Insertion(s)
Carried in Construct
P{UASp-GFP-pav.DEAD}
Also Known As
UASp-GFP-PavDEAD
Key Links
Transgenic product class
missense_variant
(Minestrini et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Minestrini et al., 2002)
Mutagen
in vitro construct
(Minestrini et al., 2002)
Progenitor genotype
Carried in construct
P{UASp-GFP-pav.DEAD}
Cytology
Description

UASp regulatory sequences drive expression of an inactive form of pav (carries amino acid replacement G131E in the ATP-binding site of the motor domain), with a mutation in tagged at the N-terminal end with mGFP6.

(Minestrini et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
pav
Tagged with
mGFP6
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Females expressing pavDEAD.Scer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16 are completely sterile and do not lay any eggs. Egg chambers rarely develop beyond stage 10 in these females. Egg chambers containing 32 cells are often seen in the ovaries of females expressing pavDEAD.Scer\UAS.P\T.T:Avic\GFP-m6 under the control of Scer\GAL4mat.αTub67C.T:Hsim\VP16. Defects in oocyte positioning are seen in early stage egg chambers.

      (Minestrini et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pavDEAD.Scer\UAS.P\T.T:Avic\GFP-m6
      pavDEAD.UASp.mGFP6
      Name Synonyms
      Secondary FlyBase IDs
        References (4)