FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\mil1
Open Close
General Information
Symbol
Dmel\mil1
Species
D. melanogaster
Name
FlyBase ID
FBal0147015
Feature type
allele
Associated gene
Dmel\mil
Associated Insertion(s)
P{GAL4}mil1
Carried in Construct
Also Known As
D0283, milkah-1
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Dubnau et al., 2003)
Progenitor genotype
Associated Insertion(s)
P{GAL4}mil1
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{GAL4}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Tarsal and antennal structures are normal in mil1 flies.

      The courtship index of naive mil1 males is lower than that of CantonS controls.

      Mutant males show can form immediate memory in a courtship suppression paradigm (CCSP), with the courtship index being reduced immediately after conditioning, but have a significant reduction in the learning index one day after training compared to immediately after training, indicating a defect in long-term memory.

      (Kuzin et al., 2014)

      Homozygous mil1 mutant flies do not show any change in sensitivity to ethanol vapor compared to controls.

      (Berger et al., 2008)

      In memory tests, mutants perform at 101% of wild-type after a single training session, at 21% after spaced training.

      (Dubnau et al., 2003)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      mil1, ssa40ahm has visible phenotype

      (Kuzin et al., 2014)
      Phenotype Manifest In
      Other
      Statement
      Reference

      mil1, ssa40ahm has tarsal segment phenotype

      (Kuzin et al., 2014)

      mil1, ssa40ahm has arista phenotype

      (Kuzin et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The arista of ssa40ahm mil1 double mutant flies show homeotic transformation into an unsegmented tarsus. The tarsal structures of the double mutants show altered segment fusion.

      (Kuzin et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      D0283
      (van Swinderen et al., 2009, Berger et al., 2008, Dubnau et al., 2003)
      mil1
      milkah
      (Berger et al., 2008)
      milkah-1
      (Kuzin et al., 2014, Berger et al., 2008)
      Name Synonyms
      Milkah-1
      (Dubnau et al., 2003)
      Secondary FlyBase IDs
        References (4)