FlyBase Allele Report: Dmel\Nedd4[EY00500]

General Information

Symbol

Dmel\Nedd4^EY00500

Species

D. melanogaster

Name

FlyBase ID

FBal0147733

Feature type

allele

Associated gene

Dmel\Nedd4

Associated Insertion(s)

P{EPgy2}Nedd4^EY00500

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EPgy2}Nedd4^EY00500

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:17,533,127..17,533,127 [+]

(Keleman et al., 2005, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates severe acute respiratory syndrome

modeled by HCoV-SARS\3a^{UAS.CUHK-W1.EGFP}

(Wong et al., 2005)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Nedd4[+]/Nedd4^EY00500 is a non-enhancer of chemical sensitive | adult stage phenotype of Otud6^C183A

(Villa et al., 2024)

Nedd4[+]/Nedd4^EY00500 is a non-enhancer of increased mortality | adult stage phenotype of Otud6^C183A

(Villa et al., 2024)

Nedd4^EY00500/Scer\GAL4^elav.PLu is a non-enhancer of abnormal neuroanatomy | embryonic stage 16 phenotype of robo1¹, sli²

(Keleman et al., 2005)

Scer\GAL4^insc-Mz1407/Nedd4^EY00500 is a non-enhancer of abnormal neuroanatomy | embryonic stage 16 phenotype of robo1¹, sli²

(Keleman et al., 2005)

NOT Suppressor of

Statement

Reference

Nedd4[+]/Nedd4^EY00500 is a non-suppressor of chemical sensitive | adult stage phenotype of Otud6^C183A

(Villa et al., 2024)

Nedd4[+]/Nedd4^EY00500 is a non-suppressor of increased mortality | adult stage phenotype of Otud6^C183A

(Villa et al., 2024)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

Nedd4^EY00500/Scer\GAL4^elav.PLu is a non-enhancer of larval longitudinal connective | embryonic stage 16 phenotype of robo1¹, sli²

(Keleman et al., 2005)

Nedd4^EY00500/Scer\GAL4^elav.PLu is a non-enhancer of commissure | embryonic stage 16 phenotype of robo1¹, sli²

(Keleman et al., 2005)

Scer\GAL4^insc-Mz1407/Nedd4^EY00500 is a non-enhancer of larval longitudinal connective | embryonic stage 16 phenotype of robo1¹, sli²

(Keleman et al., 2005)

Scer\GAL4^insc-Mz1407/Nedd4^EY00500 is a non-enhancer of commissure | embryonic stage 16 phenotype of robo1¹, sli²

(Keleman et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of Nedd4^EY00500 under the control of either Scer\GAL4^elav.PLu or Scer\GAL4¹⁴⁰⁷ does not enhance the midline crossing phenotype seen in transheterozygous sli² robo¹ stage 16 embryos.

(Keleman et al., 2005)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

15289

y¹ w^67c23; P{EPgy2}Nedd4^EY00500

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Nedd4^EP

(Villa et al., 2024)

Nedd4^EY00500

(Zhu et al., 2017, Wong et al., 2005)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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