FlyBase Allele Report: Dmel\sqz[UAS.cAa]

General Information

Symbol

Dmel\sqz^UAS.cAa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Allan

FlyBase ID

FBal0150238

Feature type

allele

Associated gene

Dmel\sqz

Associated Insertion(s)

Carried in Construct

P{UAS-sqz.A}

Also Known As

UAS-sqz, UASsqz

Key Links

Transgenic product class

cDNA

(Allan et al., 2003)

wild_type

(Allan et al., 2003)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Allan et al., 2003)

wild_type

(Allan et al., 2003)

Mutagen

in vitro construct

(Allan et al., 2003, Allan et al., 2003)

Progenitor genotype

Carried in construct

P{UAS-sqz.A}

Cytology

Description

UAS sequences drive expression of a sqz cDNA.

(Allan et al., 2003)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

sqz

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates cancer

modeled by HPV18\E6^UAS.Tag:MYC, Hsap\UBE3A^UAS.cRa

(Collins et al., 2023)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^rn.PU

(Percival-Smith et al., 2013)

Phenotype Manifest In

tarsal segment, with Scer\GAL4^rn-GAL4-13

(Félix et al., 2007)

wing hinge, with Scer\GAL4^rn-GAL4-13

(Félix et al., 2007)

wing margin, with Scer\GAL4^rn.PU

(Percival-Smith et al., 2013)

Detailed Description

Statement

Reference

Expression of sqz^Scer\UAS.cAa under the control of Scer\GAL4^rn.PU results in nicks along the wing margin.

(Percival-Smith et al., 2013)

The wing hinge is reduced in sqz^Scer\UAS.cAa; Scer\GAL4^rn-GAL4-13 adults and tarsal segments are partially deleted.

(Félix et al., 2007)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

sqz^UAS.cAa, Scer\GAL4^GMR.PU is an enhancer of visible | adult stage phenotype of HPV18\E6^UAS.Tag:MYC, Hsap\UBE3A^UAS.cRa, Scer\GAL4^GMR.PU

(Collins et al., 2023)

Phenotype Manifest In

Enhancer of

Statement

Reference

sqz^UAS.cAa, Scer\GAL4^GMR.PU is an enhancer of eye phenotype of HPV18\E6^UAS.Tag:MYC, Hsap\UBE3A^UAS.cRa, Scer\GAL4^GMR.PU

(Collins et al., 2023)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of sqz^Scer\UAS.cAa and nab^Scer\UAS.cCa under the control of Scer\GAL4^elav-C155 results in a significant increase in the number of SELK neurons.

(Losada-Pérez et al., 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

sqz^UAS.cAa/Scer\GAL4^ap-md544 rescues sqz^GAL4

(Allan et al., 2003)

sqz^UAS.cAa/Scer\GAL4^sqz-GAL4 rescues sqz^GAL4

(Allan et al., 2003)

sqz^UAS.cAa/Scer\GAL4^ap-md544 rescues sqz^GAL4

(Allan et al., 2003)

sqz^UAS.cAa/Scer\GAL4^sqz-GAL4 rescues sqz^GAL4

(Allan et al., 2003)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

36497

w^*; P{UAS-sqz.A}7-3/CyO; P{neoFRT}82B sqz^ie/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

sqz^Scer\UAS.cAa

sqz^UAS.cAa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Allan

(Allan et al., 2003, Allan et al., 2003)

Secondary FlyBase IDs

References (11)

Report Sections

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